Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 6/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046177 | 0.85 | MAPK1 (0.60) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| Hydrochloric Acid SCHEMBL3044343 | 0.84 | MAPK1 (0.59) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| SCHEMBL14693641 | 0.83 | KDM4E (0.58) | ALDH1A1LMNAKDM4EHPGDHRH1 | |
| SCHEMBL3040648 | 0.82 | PTAFR (0.69) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| SCHEMBL10531167 | 0.82 | NOTUM (0.65) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| SCHEMBL3043915 | 0.82 | MAPK1 (0.48) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| Methoxyamine SCHEMBL3146562 | 0.81 | MAPK1 (0.55) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| Hydrochloric Acid SCHEMBL3045212 | 0.81 | MEN1 (0.47) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| SCHEMBL3043670 | 0.81 | MAPK1 (0.47) | ALDH1A1LMNAKDM4EHPGDNOTUM | |
| SCHEMBL3040945 | 0.80 | MAPK1 (0.52) | ALDH1A1LMNAKDM4EHPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243778-B1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| EP-2243778-A1 | PIPERIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | HRH4, HRH3, HRH2 | ALDH1A1 1730/4885LMNA 4870/4885KDM4E 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.