Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215810 | 1.00 | HDAC6 (0.48) | HDAC6HDAC1HDAC3HDAC2KDR | |
| SCHEMBL24216144 | 0.98 | HDAC6 (0.48) | HDAC6HDAC1HDAC3HDAC2KDR | |
| SCHEMBL30460258 | 0.98 | HDAC6 (0.48) | HDAC6HDAC1HDAC3HDAC2KDR | |
| SCHEMBL30409859 | 0.91 | HDAC6 (0.40) | HDAC6 | |
| SCHEMBL24216889 | 0.91 | HDAC6 (0.40) | HDAC6 | |
| SCHEMBL25352253 | 0.91 | HDAC6 (0.40) | HDAC6HDAC1KDREPHB4TEK | |
| SCHEMBL25350111 | 0.91 | HDAC6 (0.47) | HDAC6HDAC1KDREPHB4TEK | |
| SCHEMBL25351450 | 0.91 | LRRK2 (0.40) | HDAC6HDAC1 | |
| SCHEMBL24217084 | 0.90 | LRRK2 (0.42) | HDAC6HDAC1 | |
| SCHEMBL30409371 | 0.90 | LRRK2 (0.42) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |