Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24216702 | 1.00 | HDAC6 (0.53) | HDAC6HDAC1CDC7ROCK2GSK3B | |
| SCHEMBL25351919 | 0.90 | HDAC1 (0.49) | HDAC6HDAC1ROCK2GSK3BPIM1 | |
| SCHEMBL24216706 | 0.89 | HDAC6 (0.51) | HDAC6HDAC1CDC7KDRESRRG | |
| SCHEMBL30410124 | 0.89 | HDAC6 (0.51) | HDAC6HDAC1CDC7KDRESRRG | |
| SCHEMBL25354963 | 0.88 | HDAC1 (0.50) | HDAC6HDAC1CDC7ROCK2GSK3B | |
| SCHEMBL25351011 | 0.88 | HDAC6 (0.51) | HDAC6HDAC1CDC7ROCK2GSK3B | |
| SCHEMBL25349979 | 0.86 | HDAC6 (0.49) | HDAC6HDAC1KDR | |
| SCHEMBL25351724 | 0.86 | HDAC6 (0.53) | HDAC6HDAC1CDC7KDR | |
| SCHEMBL25351125 | 0.85 | HDAC1 (0.52) | HDAC6HDAC1 | |
| SCHEMBL24215783 | 0.84 | HDAC6 (0.49) | HDAC6HDAC1CDC7KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| EP-4185586-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116133658-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-05-16 | — | — | CN | disclosed |