Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30410572 | 0.99 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30411049 | 0.94 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2CDK1FLT3 | |
| SCHEMBL30410615 | 0.92 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30409308 | 0.91 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30410510 | 0.90 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30410622 | 0.90 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30409893 | 0.90 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30410429 | 0.90 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30411040 | 0.90 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 | |
| SCHEMBL30410674 | 0.90 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2YTHDC1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4178959-A1 | NITROGEN HETEROCYCLIC CYTOKININ DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2023-05-17 | — | — | EP | disclosed |