Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764688 | 1.00 | ITGA5 (0.46) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL30412293 | 0.94 | ITGA5 (0.47) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL20792438 | 0.94 | ITGA5 (0.47) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL20764702 | 0.91 | ITGA5 (0.46) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL23679179 | 0.87 | SLC6A2 (0.47) | ITGA5ITGB6ITGB8HTTMTOR | |
| SCHEMBL20764736 | 0.87 | MTOR (0.48) | HTTLMNAMTORHPGDNPC1 | |
| SCHEMBL30410997 | 0.87 | MTOR (0.48) | HTTLMNAMTORHPGDNPC1 | |
| SCHEMBL19283611 | 0.86 | ITGA5 (0.46) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL20743289 | 0.86 | ITGA5 (0.45) | ITGA5ITGB6ITGB8RAF1HTT | |
| SCHEMBL20743024 | 0.86 | ITGA5 (0.45) | ITGA5ITGB6ITGB8RAF1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | claimed |
| CN-111372928-B | Benzimidazole derivatives as potassium channel inhibitors | 阿塞西翁制药公司 | 2023-05-16 | — | — | CN | disclosed |