Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24108255 | 1.00 | KDM4E (0.53) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL22118349 | 0.83 | CYP1A1 (0.45) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL30411254 | 0.82 | SMN1; SMN2 (0.44) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL24107946 | 0.82 | SMN1; SMN2 (0.44) | KDM4ENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL24108254 | 0.82 | DRD1 (0.41) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL24108500 | 0.82 | SCN10A (0.41) | RIPK1NPY5R | |
| SCHEMBL30339975 | 0.82 | SCN10A (0.41) | RIPK1NPY5R | |
| SCHEMBL24107996 | 0.79 | KDM4E (0.49) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL30340295 | 0.79 | KDM4E (0.49) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL26045173 | 0.78 | NPC1 (0.48) | KDM4ENPC1RAB9AMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157393-A | Inhibitors of APOL1 and uses thereof | 弗特克斯药品有限公司 | 2023-05-23 | — | — | CN | disclosed |