Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1703501 | 0.84 | PTPN2 (0.58) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL10470287 | 0.77 | ABCC1 (0.58) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL13764835 | 0.77 | PTPN2 (0.72) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL10741969 | 0.75 | PTPN2 (0.64) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL1704195 | 0.74 | PTK2 (0.71) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL5836577 | 0.74 | PTPN2 (1.00) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL5550829 | 0.74 | PTPN2 (0.68) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL4141410 | 0.73 | PTPN2 (0.62) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL19237020 | 0.71 | PTPN2 (0.64) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 | |
| SCHEMBL14231616 | 0.71 | PTPN2 (0.58) | PTPN2PTPRBPTPN6ABCC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143197-A1 | THIENO PYRIMIDINES AS FERROPORTIN INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |