Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.76 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | MIF | P14174 | 4/20 | 0.60 |
| ▸ | ACHE | P22303 | 6/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927342 | 1.00 | MAOB (0.76) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL28962157 | 0.87 | MAOB (0.76) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL30413102 | 0.87 | MAOB (0.76) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL14524721 | 0.87 | MAOB (1.00) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL5582417 | 0.87 | MAOB (1.00) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL5582418 | 0.87 | MAOB (1.00) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL30413515 | 0.86 | MAOB (0.74) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL28927486 | 0.86 | MAOB (0.74) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL30412163 | 0.85 | MAOB (0.78) | MAOBMAOACYP19A1MIFACHE | |
| SCHEMBL28927347 | 0.85 | MAOB (0.78) | MAOBMAOACYP19A1MIFACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417871-B | Double spiro pyrrolospirone oxindole compound, synthesis method and antifungal activity thereof | 成都理工大学 | 2023-06-02 | — | — | CN | disclosed |