Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.72 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.59 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | LYN | P07948 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15155196 | 1.00 | BTK (0.72) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL24196512 | 0.97 | BTK (0.68) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL16075015 | 0.95 | BTK (0.77) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL22720726 | 0.94 | BTK (0.64) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL30718270 | 0.94 | BTK (0.64) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL22737537 | 0.94 | BTK (0.63) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL30415927 | 0.93 | BTK (0.65) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL24196799 | 0.93 | BTK (0.65) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL15155190 | 0.92 | BTK (0.75) | BTKEGFRNUDT14NUDT5LCK | |
| SCHEMBL30954861 | 0.92 | BTK (0.75) | BTKEGFRNUDT14NUDT5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134028-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-05-16 | — | — | CN | disclosed |