Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.88 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.88 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.88 |
| ▸ | KIT | P10721 | 2/20 | 0.88 |
| ▸ | SRC | P12931 | 2/20 | 0.88 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.88 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.88 |
| ▸ | CIT | O14578 | 1/20 | 0.88 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.88 |
| ▸ | GAK | O14976 | 1/20 | 0.88 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.88 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.88 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.88 |
| ▸ | STK17B | O94768 | 1/20 | 0.88 |
| ▸ | STK10 | O94804 | 1/20 | 0.88 |
| ▸ | ABL1 | P00519 | 1/20 | 0.88 |
| ▸ | LCK | P06239 | 1/20 | 0.88 |
| ▸ | FYN | P06241 | 1/20 | 0.88 |
| ▸ | YES1 | P07947 | 1/20 | 0.88 |
| ▸ | LYN | P07948 | 1/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Canertinib SCHEMBL29368458 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL54837 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| SCHEMBL95068 | 0.93 | EGFR (0.84) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL29623482 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL29655741 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL2141065 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL30436576 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL2052123 | 0.93 | EGFR (1.00) | EGFRERBB2ERBB4KITSRC | |
| Canertinib SCHEMBL731396 | 0.92 | EGFR (0.97) | EGFRERBB2ERBB4KITSRC | |
| SCHEMBL25216586 | 0.91 | EGFR (0.81) | EGFRERBB2ERBB4KITSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134022-B | ATR inhibitors and uses thereof | 上海德琪医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116134022-A | ATR inhibitors and uses thereof | 上海德琪医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |