Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2122685 | 0.86 | ACE (0.48) | ACERENLMNAKDM4EF2 | |
| SCHEMBL2113641 | 0.86 | ACE (0.48) | ACERENLMNAKDM4EF2 | |
| SCHEMBL29609766 | 0.86 | ACE (0.51) | ACEREN | |
| SCHEMBL31688030 | 0.85 | DPP7 (0.44) | ACERENLMNAKDM4EF2 | |
| SCHEMBL30471842 | 0.84 | ACE (0.41) | ACEREN | |
| SCHEMBL30817477 | 0.84 | ACE (0.49) | ACEREN | |
| SCHEMBL30423512 | 0.84 | ACE (0.49) | ACEREN | |
| SCHEMBL7758744 | 0.83 | ACE (0.64) | ACERENLMNAKDM4EF2 | |
| SCHEMBL29802029 | 0.82 | ACE (0.48) | ACEREN | |
| SCHEMBL29547044 | 0.82 | ACE (0.53) | ACERENLMNAKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159461-B | Synthesis method of cetrorelix | 开封明仁药业有限公司 | 2023-03-10 | — | — | CN | disclosed |