Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.72 |
| ▸ | CLK1 | P49759 | 1/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.70 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.70 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.70 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068810 | 1.00 | DYRK1A (0.72) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL20068739 | 0.84 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL20068741 | 0.84 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL30417040 | 0.84 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL20069003 | 0.83 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL29159565 | 0.83 | DYRK1A (0.80) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL30416708 | 0.83 | DYRK1A (0.80) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL20068809 | 0.82 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL30416556 | 0.82 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 | |
| SCHEMBL30416134 | 0.82 | DYRK1A (1.00) | DYRK1ACLK1CLK2DYRK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843879-B | Benzothiazole derivatives as DYRK1 inhibitors | 药物治疗股份有限公司 | 2023-05-02 | — | — | CN | disclosed |