Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008487 | 0.96 | MEN1 (0.54) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL14469419 | 0.95 | MEN1 (0.55) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL8500626 | 0.95 | MEN1 (0.55) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL31419831 | 0.95 | MEN1 (0.51) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL9574209 | 0.93 | MEN1 (0.53) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL6879618 | 0.91 | KDM4C (0.58) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL1008376 | 0.90 | MEN1 (0.53) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL14411450 | 0.89 | MEN1 (0.50) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL13423730 | 0.89 | MEN1 (0.50) | MEN1KMT2AKDM4COPRM1OPRK1 | |
| SCHEMBL10683709 | 0.89 | KMT2A (0.56) | MEN1KMT2AKDM4COPRM1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |