Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 4/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24103634 | 1.00 | SSTR4 (0.43) | SSTR4SYKBACE1SOS1HDAC1 | |
| SCHEMBL30075039 | 0.87 | SSTR4 (0.39) | SSTR4BACE1HDAC1HDAC8HDAC6 | |
| SCHEMBL21566105 | 0.87 | SSTR4 (0.39) | SSTR4BACE1HDAC1HDAC8HDAC6 | |
| SCHEMBL20580580 | 0.84 | SSTR4 (0.38) | SSTR4SYKSOS1PAX8MEN1 | |
| SCHEMBL29863332 | 0.82 | SSTR4 (0.35) | SSTR4SYKBACE1PAX8BACE2 | |
| SCHEMBL16753375 | 0.82 | SSTR4 (0.35) | SSTR4SYKBACE1PAX8BACE2 | |
| SCHEMBL24102996 | 0.82 | SSTR4 (0.38) | SSTR4SYKBACE1SOS1 | |
| SCHEMBL24103619 | 0.81 | SSTR4 (0.37) | SSTR4SYKSOS1PAX8NPC1 | |
| SCHEMBL22980358 | 0.81 | SSTR4 (0.37) | SSTR4SYKSOS1PAX8 | |
| SCHEMBL23107325 | 0.81 | SSTR4 (0.37) | SSTR4SYKBACE1SOS1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209664-A | Small molecule modulators of IL-17 | 利奥制药有限公司 | 2023-06-02 | — | — | CN | disclosed |