Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257294 | 1.00 | CHEK1 (0.39) | CHEK1FLT3PLK3DAOKDM4E | |
| SCHEMBL3465338 | 0.77 | DAO (0.38) | CHEK1FLT3PLK3DAOKDM4E | |
| SCHEMBL16593421 | 0.71 | KDM5A (0.45) | CHEK1DAOKDM4EMEN1ALDH1A1 | |
| SCHEMBL1944275 | 0.69 | LRRK2 (0.41) | CHEK1DAOAXLPRKCI | |
| SCHEMBL18529490 | 0.69 | DYRK1A (0.36) | CHEK1FLT3PLK3LMNACYP3A4 | |
| SCHEMBL30406172 | 0.69 | LRRK2 (0.41) | CHEK1DAOAXLPRKCI | |
| SCHEMBL29760851 | 0.69 | DYRK1A (0.36) | CHEK1FLT3PLK3LMNACYP3A4 | |
| SCHEMBL15866141 | 0.68 | CHEK1 (0.66) | CHEK1FLT3PLK3DAOCYP1A2 | |
| SCHEMBL30040295 | 0.68 | CHEK1 (0.66) | CHEK1FLT3PLK3DAOCYP1A2 | |
| SCHEMBL19997517 | 0.68 | DAO (0.41) | DAOKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058798-A | Bicyclic TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-4436957-A1 | THERAPEUTIC INDAZOLE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| CN-118302411-A | Therapeutic indazole compounds and methods of use thereof for the treatment of cancer | 基因泰克公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023097195-A1 | THERAPEUTIC INDAZOLE COMPOUNDS AND METHODS OF USE IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2023-06-01 | — | — | WO | disclosed |