Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29069633 | 1.00 | GSTP1 (0.41) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL29069650 | 0.81 | GSTP1 (0.41) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL25395095 | 0.79 | CCNE1 (0.33) | TDP1ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL23070919 | 0.78 | CYP3A4 (0.46) | TDP1ALDH1A1MAPK1HSD17B10LMNA | |
| SCHEMBL30320915 | 0.76 | GSTP1 (0.40) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL29069652 | 0.76 | GSTP1 (0.40) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL22440531 | 0.73 | KMT2A (0.42) | GSTP1GSTM2CXCR1CXCR2ALDH1A1 | |
| SCHEMBL30321002 | 0.72 | GSTP1 (0.39) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL29069631 | 0.72 | GSTP1 (0.39) | GSTP1GSTM2CXCR1CXCR2ABL1 | |
| SCHEMBL18319841 | 0.72 | KMT2A (0.45) | GSTP1GSTM2CXCR1CXCR2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323566-B | Sulfanone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-116323566-A | Sulfanone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-06-23 | — | — | CN | disclosed |