Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.45 |
| ▸ | PI4KA | P42356 | 11/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 11/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.43 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242699 | 1.00 | HDAC6 (0.47) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25211080 | 0.94 | HDAC6 (0.47) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL30424920 | 0.94 | HDAC6 (0.47) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25252672 | 0.92 | PIK3CA (0.43) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25267881 | 0.88 | PIK3CA (0.54) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25213667 | 0.88 | PIK3CA (0.45) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL30425066 | 0.88 | HDAC6 (0.50) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25216541 | 0.88 | HDAC6 (0.50) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL25243287 | 0.87 | PIK3CA (0.39) | HDAC6PIK3CAPI4KAPI4KBPIK3CD | |
| SCHEMBL30425271 | 0.87 | PIK3CA (0.39) | HDAC6PIK3CAPI4KAPI4KBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | disclosed |