Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 20/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22221967 | 1.00 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL24026373 | 1.00 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL19182300 | 0.88 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL19180965 | 0.87 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL19180964 | 0.87 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL26245461 | 0.86 | ERBB2 (0.76) | ERBB2EGFR | |
| SCHEMBL19181013 | 0.85 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL29434938 | 0.85 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL29926978 | 0.85 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL19181012 | 0.85 | ERBB2 (1.00) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113271950-B | Pyrimidine compound or salt thereof | 大鹏药品工业株式会社 | 2024-04-30 | — | — | CN | disclosed |
| EP-4183395-A1 | PYRIMIDINE COMPOUND-CONTAINING COMBINATION TO BE USED IN TUMOR TREATMENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2023-05-24 | — | — | EP | disclosed |