Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.57 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25254521 | 1.00 | TSHR (0.59) | TSHRHPGDALDH1A1MAPK1RECQL | |
| SCHEMBL30424253 | 0.88 | HDAC6 (0.61) | ALDH1A1HDAC6MMP13TDP1NPC1 | |
| SCHEMBL25250743 | 0.88 | HDAC6 (0.61) | ALDH1A1HDAC6MMP13TDP1NPC1 | |
| SCHEMBL30425008 | 0.84 | SMN1; SMN2 (0.64) | TSHRALDH1A1HDAC6MMP13TDP1 | |
| SCHEMBL25211577 | 0.84 | SMN1; SMN2 (0.64) | TSHRALDH1A1HDAC6MMP13TDP1 | |
| SCHEMBL25251072 | 0.83 | HDAC6 (0.62) | TSHRALDH1A1HDAC6MMP13TDP1 | |
| SCHEMBL30425115 | 0.83 | HDAC6 (0.62) | TSHRALDH1A1HDAC6MMP13TDP1 | |
| SCHEMBL25214603 | 0.83 | HDAC6 (0.62) | ALDH1A1HDAC6TDP1NPC1RAB9A | |
| SCHEMBL30425006 | 0.83 | HDAC6 (0.62) | ALDH1A1HDAC6TDP1NPC1RAB9A | |
| SCHEMBL25268953 | 0.82 | HDAC6 (0.60) | ALDH1A1HDAC6MMP13TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | claimed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | claimed |
| CN-116157398-B | Oxadiazole-based selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-116157398-A | 2- (4- ((5- (benzo [ b ] thiophen-3-yl) -1H-tetrazol-1-yl) methyl) phenyl) -5- (difluoromethyl) -1,3, 4-oxadiazole derivatives and similar compounds as selective inhibitors of histone deacetylase 6 (HDAC 6) for the treatment of, for example, peripheral neuropathy | 意大发马克股份公司 | 2023-05-23 | — | — | CN | disclosed |