Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21873532 | 1.00 | PARP1 (0.39) | PARP1GRM2CSF1RGPR52SMN1; SMN2 | |
| SCHEMBL30428268 | 0.91 | GRM2 (0.39) | GRM2CSF1RGPR52SMN1; SMN2MEN1 | |
| SCHEMBL21873618 | 0.91 | GRM2 (0.39) | GRM2CSF1RGPR52SMN1; SMN2MEN1 | |
| SCHEMBL21873488 | 0.85 | SLC5A1 (0.39) | SMN1; SMN2RAB9A | |
| SCHEMBL30429049 | 0.85 | SLC5A1 (0.39) | SMN1; SMN2RAB9A | |
| SCHEMBL21935399 | 0.85 | ADORA2A (0.43) | CHRNA7CHRM1KCNH2NPC1RAB9A | |
| SCHEMBL21935658 | 0.84 | ADORA2A (0.42) | SMN1; SMN2KMT2ACHRNA7CHRM1 | |
| SCHEMBL31668954 | 0.82 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL21873403 | 0.82 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL21873484 | 0.82 | CHRM1 (0.54) | CHRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709401-B | Heterocyclic compounds | 武田药品工业株式会社 | 2023-06-13 | — | — | CN | disclosed |