Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.45 |
| ▸ | CCNC | P24863 | 8/20 | 0.40 |
| ▸ | CDK8 | P49336 | 8/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21873385 | 1.00 | CHRM1 (0.45) | CHRM1CCNCCDK8GRM2MAPK8 | |
| SCHEMBL21873501 | 0.89 | CHRM1 (0.45) | CHRM1CCNCCDK8GRM2PIM1 | |
| SCHEMBL21873365 | 0.89 | CHRM1 (0.49) | CHRM1GRM2MET | |
| SCHEMBL30428197 | 0.89 | CHRM1 (0.49) | CHRM1GRM2MET | |
| SCHEMBL19932610 | 0.88 | CHRM1 (0.46) | CHRM1CCNCCDK8GRM2MAPK8 | |
| SCHEMBL21873604 | 0.85 | BRD4 (0.38) | CHRM1 | |
| SCHEMBL30428362 | 0.85 | BRD4 (0.38) | CHRM1 | |
| SCHEMBL30427998 | 0.85 | CHRM1 (0.47) | CHRM1 | |
| SCHEMBL21873516 | 0.85 | CHRM1 (0.47) | CHRM1 | |
| SCHEMBL21935357 | 0.83 | CHRM1 (0.64) | CHRM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709401-B | Heterocyclic compounds | 武田药品工业株式会社 | 2023-06-13 | — | — | CN | disclosed |