Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CCNC | P24863 | 8/20 | 0.43 |
| ▸ | CDK8 | P49336 | 8/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21873419 | 1.00 | PIM1 (0.47) | PIM1PIM2GRM2CHRM1CCNC | |
| SCHEMBL21873507 | 0.85 | PIM1 (0.45) | PIM1PIM2GRM2CHRM1CCNC | |
| SCHEMBL30427817 | 0.85 | PIM1 (0.45) | PIM1PIM2GRM2CHRM1CCNC | |
| SCHEMBL21935669 | 0.83 | CHRM1 (0.64) | CHRM1CCNCCDK8 | |
| SCHEMBL21873408 | 0.83 | BRD4 (0.38) | — | |
| SCHEMBL30428105 | 0.83 | BRD4 (0.38) | — | |
| SCHEMBL31668927 | 0.80 | CHRM1 (0.60) | CHRM1 | |
| SCHEMBL21873428 | 0.80 | CHRM1 (0.60) | CHRM1 | |
| SCHEMBL22367841 | 0.78 | PIM1 (0.47) | PIM1PIM2CHRM1CCNCCDK8 | |
| SCHEMBL21873576 | 0.77 | BRD4 (0.37) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709401-B | Heterocyclic compounds | 武田药品工业株式会社 | 2023-06-13 | — | — | CN | disclosed |