⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388050 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL8131222 | 0.95 | — | — | |
| SCHEMBL8131224 | 0.95 | — | — | |
| SCHEMBL15233589 | 0.74 | — | — | |
| SCHEMBL7556186 | 0.70 | — | — | |
| SCHEMBL9892490 | 0.70 | — | — | |
| SCHEMBL9512452 | 0.70 | — | — | |
| SCHEMBL1123886 | 0.70 | — | — | |
| SCHEMBL8744314 | 0.67 | — | — | |
| SCHEMBL7746310 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405231-B2 | Anticancer agents; inhibitors of the HER-signaling pathway with decreased toxicity, better solubility and improved pharmacokinetic profile; e.g. 1-[4-(4-(2-[(E)-2-(4-Methanesulfinyl-phenyl)-vinyl]-oxazol-4-ylmethoxy)-phenyl)-butyl]-1H-[1,2,3]triazole | HOFFMANN-LA ROCHE INC. (US) | 2008-07-29 | — | — | US | claimed |
| US-7235574-B2 | Pentafluorosulfanyl compounds | HOFFMANN-LA ROCHE INC. (US) | 2007-06-26 | — | — | US | claimed |
| EP-1725549-A1 | PENTAFLUOROSULFANYL COMPOUNDS, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-29 | — | — | EP | claimed |
| EP-1725551-A1 | OXIDIZED THIOETHER DERIVATIVES OF STYRYL-AZOLES AND THEIR USE AS HER TYROSINE KINASES INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-29 | — | — | EP | claimed |
| WO-2005095388-A1 | PENTAFLUOROSULFANYL COMPOUNDS, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-13 | — | — | WO | claimed |
| WO-2005095393-A1 | OXIDIZED THIOETHER DERIVATIVES OF STYRYL-AZOLES AND THEIR USE AS HER TYROSINE KINASES INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-13 | — | — | WO | claimed |
| US-20050203064-A1 | Novel oxidized thioether derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-15 | — | — | US | claimed |
| US-20050197370-A1 | Novel pentafluorosulfanyl compounds | HOFFMANN-LA ROCHE INC. | 2005-09-08 | — | — | US | claimed |
| CN-1501542-A | Lithium secondary battery and a method for preparing the same | 三星SDI株式会社 | 2004-06-02 | — | — | CN | claimed |
| EP-0665237-B1 | Process for the preparation of phosphorus containing dicarboxylic acid esters and dicarboxylic acids | CLARIANT GMBH (DE) | 2001-05-30 | — | — | EP | claimed |
| US-5693842-A | Process for preparing phosphorus-containing dicarboxylic acids alkyl esters thereof | HOECHST AG (DE) | 1997-12-02 | — | — | US | claimed |
| US-20260137698-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | JOINT STOCK CO «BIOCAD» (RU) | 2026-05-21 | — | — | US | disclosed |
| EP-4592283-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | Joint Stock Company "Biocad" (RU) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024063670-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | Акционерное общество "БИОКАД" | 2024-03-28 | — | — | WO | disclosed |
| CN-115925421-A | Photocuring 3D printing mechanoluminescence ceramic and preparation method and application thereof | 深圳大学 | 2023-04-07 | — | — | CN | disclosed |
| EP-0357336-A2 | Method for detection of specific nucleic acid sequences | SYNTEX (U.S.A.) INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0300796-A2 | Amplification method for polynucleotide assays | SYNTEX (U.S.A.) INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4294719-A | ALSO URETONE-IMINE GROUPS; HIGHLY SELECTIVE, REMOVABLE CATALYST MATRIX | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4067820-A | PHOSPHOROUS CONTAINING | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
| US-4052484-A | SUBSTITUTED CYCLIC PHOSPHINE OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |