Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 17/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557509 | 1.00 | MAP3K5 (0.46) | MAP3K5PSEN1ABL1MAP3K6 | |
| SCHEMBL28653758 | 0.84 | MAP3K5 (0.39) | MAP3K5MAP3K6 | |
| SCHEMBL20557293 | 0.83 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL30433867 | 0.83 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL20557175 | 0.81 | MAP3K5 (0.46) | MAP3K5MAP3K6 | |
| SCHEMBL30433991 | 0.81 | MAP3K5 (0.46) | MAP3K5MAP3K6 | |
| SCHEMBL25619915 | 0.81 | MAP3K5 (0.40) | MAP3K5MAP3K6 | |
| SCHEMBL20557545 | 0.80 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL30433534 | 0.80 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL20557450 | 0.80 | MAP3K5 (0.44) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869017-B | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2023-05-05 | — | — | CN | disclosed |