Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 19/20 | 0.52 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557566 | 1.00 | MAP3K5 (0.52) | MAP3K5AKT1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20557223 | 0.86 | MAP3K5 (0.53) | MAP3K5AKT1 | |
| SCHEMBL30433737 | 0.86 | MAP3K5 (0.53) | MAP3K5AKT1 | |
| SCHEMBL15811764 | 0.85 | MAP3K5 (0.50) | MAP3K5AKT1 | |
| SCHEMBL30433824 | 0.85 | MAP3K5 (0.50) | MAP3K5AKT1 | |
| SCHEMBL20557185 | 0.84 | MAP3K5 (0.52) | MAP3K5AKT1 | |
| SCHEMBL30656853 | 0.84 | MAP3K5 (0.52) | MAP3K5AKT1 | |
| SCHEMBL25619965 | 0.82 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL20557516 | 0.81 | MAP3K5 (0.53) | MAP3K5ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30433833 | 0.81 | MAP3K5 (0.53) | MAP3K5ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869017-B | Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2023-05-05 | — | — | CN | disclosed |