Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26139786 | 1.00 | KDM4E (0.41) | KDM4EPKMCYP3A4CYP2C8S1PR3 | |
| SCHEMBL26139795 | 1.00 | KDM4E (0.41) | KDM4EPKMCYP3A4CYP2C8S1PR3 | |
| SCHEMBL9375095 | 0.77 | KDM4E (0.31) | KDM4EPKM | |
| SCHEMBL18543770 | 0.77 | — | — | |
| SCHEMBL187083 | 0.74 | — | — | |
| SCHEMBL898237 | 0.74 | KDM4E (0.44) | KDM4EPKM | |
| SCHEMBL19321833 | 0.73 | KDM1A (0.33) | — | |
| SCHEMBL27804509 | 0.73 | PLG (0.37) | CYP3A4 | |
| SCHEMBL11416093 | 0.73 | CYP1A2 (0.43) | KDM4EPKM | |
| SCHEMBL3748819 | 0.72 | ESR2 (0.50) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081730-A1 | 4-HYDROXY-2-OXO-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXAMIDE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | TEON THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |