Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 13/20 | 0.65 |
| ▸ | JAK2 | O60674 | 7/20 | 0.65 |
| ▸ | CD69 | Q07108 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | HRH2 | P25021 | 1/20 | 0.65 |
| ▸ | CDK7 | P50613 | 1/20 | 0.65 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.65 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.65 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.65 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.65 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.65 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 5/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25170629 | 1.00 | BTK (0.65) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25176460 | 0.95 | BTK (0.65) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25173714 | 0.95 | BTK (0.66) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25169912 | 0.94 | BTK (0.71) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL30434060 | 0.94 | BTK (0.71) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25176776 | 0.92 | BTK (0.67) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25173774 | 0.90 | BTK (0.63) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25176697 | 0.90 | BTK (0.61) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL31169609 | 0.90 | BTK (0.61) | BTKJAK2CD69CYP3A4HRH2 | |
| SCHEMBL25170717 | 0.90 | BTK (0.63) | BTKJAK2CD69CYP3A4HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159532-A | Compound with BTK protein degradation activity and medical application thereof | 尤比克斯治疗公司 | 2024-06-07 | — | — | CN | disclosed |