Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25347686 | 1.00 | TRPV1 (0.36) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL25347693 | 1.00 | TRPV1 (0.36) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL14839527 | 0.76 | BCDIN3D (0.35) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL25323300 | 0.75 | TRPV1 (0.36) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL25920776 | 0.75 | TRPV1 (0.36) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL25323306 | 0.75 | TRPV1 (0.36) | TRPV1FAAHCREBBPBRD4ABL1 | |
| SCHEMBL14849720 | 0.72 | TRPV1 (0.38) | TRPV1FAAHABL1CCR4SYK | |
| Hydrochloric Acid SCHEMBL30568001 | 0.71 | TRPV1 (0.39) | TRPV1CREBBPBRD4ABL1CCR4 | |
| Hydrochloric Acid SCHEMBL21385193 | 0.71 | TRPV1 (0.39) | TRPV1CREBBPBRD4ABL1CCR4 | |
| SCHEMBL22455760 | 0.70 | KDM1A (0.43) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194111-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊生物 | 2023-05-30 | — | — | CN | disclosed |