Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146515 | 1.00 | GUSB (0.50) | GUSBCYP1A1CYP1B1CYP1A2PDE3B | |
| SCHEMBL144139 | 0.83 | BRD4 (0.56) | GUSBCYP1A1CYP1B1CYP1A2PDE3B | |
| SCHEMBL30055885 | 0.83 | BRD4 (0.56) | GUSBCYP1A1CYP1B1CYP1A2PDE3B | |
| SCHEMBL19582552 | 0.82 | GUSB (0.54) | GUSBCYP1A1CYP1B1CYP1A2KDM4E | |
| SCHEMBL348447 | 0.81 | BRD4 (0.49) | GUSBCYP1A1CYP1B1CYP1A2PDE3B | |
| SCHEMBL259473 | 0.80 | GUSB (0.67) | GUSBCYP1A1CYP1B1CYP1A2KDM4E | |
| SCHEMBL147943 | 0.79 | BRD4 (0.69) | BRD4 | |
| SCHEMBL30054393 | 0.79 | BRD4 (0.69) | BRD4 | |
| SCHEMBL20771302 | 0.78 | HPGD (0.57) | GUSBCYP1A1CYP1B1CYP1A2PDE3B | |
| SCHEMBL8499675 | 0.78 | TNKS (0.67) | GUSBCYP1A1CYP1B1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | claimed |
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |