Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.61 |
| ▸ | PARP1 | P09874 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.56 |
| ▸ | IL17A | Q16552 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | BRD1 | O95696 | 1/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149925 | 1.00 | BRD4 (0.61) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL377714 | 0.91 | BRD4 (0.57) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL15551676 | 0.88 | BRD4 (0.54) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL25694623 | 0.86 | BRD4 (0.69) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL122791 | 0.86 | PBRM1 (0.60) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL30434926 | 0.86 | PBRM1 (0.60) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL378245 | 0.85 | BRD4 (0.77) | BRD4PARP1HDAC1IL17AHDAC3 | |
| Apabetalone SCHEMBL29352238 | 0.85 | BRD4 (0.84) | BRD4PARP1HDAC1IL17AHDAC3 | |
| Apabetalone SCHEMBL145019 | 0.85 | BRD4 (0.84) | BRD4PARP1HDAC1IL17AHDAC3 | |
| SCHEMBL143261 | 0.84 | BRD4 (0.66) | BRD4PARP1HDAC1IL17AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |