Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 9/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | IL17A | Q16552 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146822 | 1.00 | PDE3B (0.50) | PDE3BPDE3AXDHBRD4HDAC1 | |
| SCHEMBL14100607 | 0.85 | PDE3B (0.48) | PDE3BPDE3AXDHBRD4HDAC1 | |
| SCHEMBL147598 | 0.83 | BRD4 (0.56) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL30434565 | 0.83 | BRD4 (0.56) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL311502 | 0.83 | PDE3B (0.48) | PDE3BPDE3AXDHBRD4HDAC1 | |
| SCHEMBL30434678 | 0.81 | BRD4 (0.46) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL145706 | 0.81 | BRD4 (0.46) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL30434546 | 0.80 | BRD4 (0.49) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL142985 | 0.80 | BRD4 (0.49) | PDE3BPDE3ABRD4HDAC1HDAC3 | |
| SCHEMBL348781 | 0.79 | BRD4 (0.48) | PDE3BPDE3ABRD4HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |