SCHEMBL30435869

SCHEMBL30435869

N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 6/20 0.56
▸ REN P00797 4/20 0.56
▸ DPP4 P27487 2/20 0.47
▸ LTA4H P09960 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ F2 P00734 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ PEPD P12955 1/20 0.46
▸ ALOX15 P16050 1/20 0.46
▸ PTGS1 P23219 1/20 0.46
▸ HTR2A P28223 1/20 0.46
▸ PTGS2 P35354 1/20 0.46
▸ HRH1 P35367 1/20 0.46
▸ THPO P40225 1/20 0.46
▸ PMP22 Q01453 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ ACE2 Q9BYF1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29834944 0.97 ACE (0.53) ACERENDPP4LTA4HKDM4E
SCHEMBL30435421 0.94 ACE (0.52) ACERENDPP4LTA4HKDM4E
SCHEMBL31083914 0.92 ACE (0.56) ACERENDPP4LTA4HKDM4E
SCHEMBL1323636 0.90 ACE (0.56) ACERENDPP4LTA4HKDM4E
SCHEMBL30434889 0.90 ACE (0.56) ACERENDPP4LTA4HKDM4E
SCHEMBL12120319 0.90 ACE (0.56) ACERENDPP4LTA4HKDM4E
SCHEMBL9471485 0.89 ACE (0.48) ACERENLTA4HKDM4EF2
SCHEMBL29689214 0.89 ACE (0.61) ACERENLTA4HKDM4EF2
SCHEMBL29379105 0.88 ACE (0.47) ACERENLTA4HKDM4EF2
SCHEMBL29666870 0.88 ACE (0.52) ACERENLTA4HKDM4EF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250134947-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS ENUMITA AS (NO) 2025-05-01 — — US claimed
EP-4426715-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS Enumita AS (NO) 2024-09-11 — — EP claimed
WO-2023080790-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS TOSOJ AS (NO) 2023-05-11 — — WO claimed
CN-122071508-A Targeting NPY polypeptide nuclide ligand and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-22 — — CN disclosed
US-20250134947-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS ENUMITA AS (NO) 2025-05-01 — — US disclosed
EP-4426715-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS Enumita AS (NO) 2024-09-11 — — EP disclosed
WO-2023080790-A1 TRI-, TETRA AND PENTAPEPTIDES, COMPOSITIONS THEREOF AND THEIR USE IN THE THERAPY OF PSORIASIS TOSOJ AS (NO) 2023-05-11 — — WO disclosed
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