SCHEMBL30436352

SCHEMBL30436352

O=C(NC1CCOCC1)c1cc(Cc2ccc(-c3cccnc3)cc2)c2cccn2n1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 15/20 0.75
DYRK1A Q13627 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21858961 1.00 CHRM1 (0.75) CHRM1DYRK1A
SCHEMBL21858980 0.95 CHRM1 (0.70) CHRM1DYRK1A
SCHEMBL30436319 0.95 CHRM1 (0.70) CHRM1DYRK1A
SCHEMBL21859031 0.91 CHRM1 (0.77) CHRM1
SCHEMBL21859042 0.86 CHRM1 (0.70) CHRM1
SCHEMBL21859103 0.86 CHRM1 (1.00) CHRM1
SCHEMBL23972139 0.85 CHRM1 (0.72) CHRM1
SCHEMBL25199149 0.84 CHRM1 (1.00) CHRM1
SCHEMBL21938755 0.84 CHRM1 (1.00) CHRM1
SCHEMBL30436448 0.84 CHRM1 (1.00) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166160-B Pyrrolopyridazine derivatives as modulators of the positive allosteric of the muscarinic M1 receptor 苏文生命科学有限公司 2023-12-19 CN claimed
EP-3867254-B1 PYRROLO-PYRIDAZINE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS SUVEN LIFE SCIENCES LTD (IN) 2023-05-31 EP disclosed