Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19202558 | 1.00 | NR1H4 (0.51) | NR1H4GPBAR1LDHAKDM4EALDH1A1 | |
| SCHEMBL20031247 | 0.88 | NR1H4 (0.52) | NR1H4GPBAR1KDM4E | |
| SCHEMBL26485417 | 0.85 | GPBAR1 (0.48) | NR1H4GPBAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL21715606 | 0.85 | NR1H4 (0.54) | NR1H4 | |
| SCHEMBL16697733 | 0.84 | GPBAR1 (0.62) | NR1H4GPBAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL30605724 | 0.84 | GPBAR1 (0.62) | NR1H4GPBAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL21195682 | 0.83 | NR1H4 (0.54) | NR1H4 | |
| SCHEMBL19899996 | 0.82 | NR1H4 (0.51) | NR1H4GPBAR1 | |
| SCHEMBL30437797 | 0.82 | NR1H4 (0.51) | NR1H4GPBAR1 | |
| SCHEMBL1930933 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1GAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-B | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | disclosed |