Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30438067 | 0.87 | PPARG (0.47) | PPARGPPARATRPV1MAPK1TLR8 | |
| SCHEMBL30438759 | 0.84 | PPARG (0.44) | PPARGPPARATRPV1MAPK1TLR8 | |
| SCHEMBL29460888 | 0.76 | PRSS1 (0.46) | PPARGMAPK1TP53CYP3A4TSHR | |
| Acridine SCHEMBL28059351 | 0.70 | MAPK1 (0.50) | PPARGPPARAMAPK1TLR8MEN1 | |
| SCHEMBL6512765 | 0.69 | TLR8 (0.43) | PPARGPPARAMAPK1TLR8TP53 | |
| SCHEMBL30604094 | 0.68 | KDM4E (0.56) | TP53MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL29091020 | 0.68 | KDM4E (0.56) | TP53MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL30604151 | 0.68 | KDM4E (0.56) | TP53MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL11970231 | 0.67 | PPARG (0.46) | PPARGPPARACYP3A4MEN1ALDH1A1 | |
| SCHEMBL30402892 | 0.67 | TLR8 (0.41) | PPARGPPARAMAPK1TLR8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | disclosed |