Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068263 | 1.00 | KDM4E (0.47) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL8980162 | 0.94 | KDM4E (0.47) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL4420731 | 0.81 | NPC1 (0.58) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL28922177 | 0.81 | GAA (0.49) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL927420 | 0.79 | PTK6 (0.41) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL30702433 | 0.79 | PTK6 (0.41) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL8980355 | 0.79 | TSHR (0.49) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL30251624 | 0.79 | NPC1 (0.56) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL8980221 | 0.79 | NPC1 (0.56) | KDM4ENPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL352444 | 0.77 | NPC1 (0.53) | KDM4ENPC1RAB9AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |