SCHEMBL30438482

SCHEMBL30438482

O=C=Nc1ccc(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.40
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TRPA1 O75762 1/20 0.35
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162877 1.00 CYP3A4 (0.40) CYP3A4ALDH1A1HPGDTDP1CES2
SCHEMBL6418213 0.86 CYP3A4 (0.46) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL15751295 0.81 CYP3A4 (0.36) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL707228 0.81 CYP3A4 (0.55) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL5266135 0.81 CYP3A4 (0.36) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL3550575 0.81 CYP3A4 (0.36) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL27480987 0.81 CYP3A4 (0.36) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL1595410 0.80 CYP3A4 (0.54) CYP3A4ALDH1A1HPGDTDP1CES2
SCHEMBL29662014 0.80 CYP3A4 (0.54) CYP3A4ALDH1A1HPGDTDP1CES2
SCHEMBL27480988 0.79 CYP3A4 (0.35) CYP3A4ALDH1A1HPGDTDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912405-A Fluothidiazuron derivative and preparation method thereof 河南省科学院高新技术研究中心 2025-05-02 CN claimed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
CN-119908364-A Cotton defoliant containing fluhiuron derivative and application thereof 河南省科学院高新技术研究中心 2025-05-02 CN disclosed
CN-119912405-A Fluothidiazuron derivative and preparation method thereof 河南省科学院高新技术研究中心 2025-05-02 CN disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
CN-118525003-A Novel heteroaryl urea compounds as KV7.2 inhibitors 伊卡根有限责任公司 2024-08-20 CN disclosed
CN-112888674-B Polycyclic compounds as soluble epoxide hydrolase inhibitors 巴塞罗那大学 2023-06-30 CN disclosed
CN-112020525-B Adducts of amine catalysts for preparing isocyanurate polymers 科思创知识产权两合公司 2023-05-16 CN disclosed