Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529514 | 1.00 | PDE2A (0.36) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL25421880 | 0.84 | PDE2A (0.39) | PDE2AMAPTALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL31529511 | 0.84 | PDE2A (0.39) | PDE2AMAPTALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL29248358 | 0.84 | PDE2A (0.39) | PDE2AMAPTALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL29220620 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL29220619 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL24775053 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL4934513 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL955811 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER | |
| SCHEMBL30108487 | 0.82 | KMT2A (0.42) | PDE2AMEN1KMT2AALOX15GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436955-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | Lario Therapeutics Limited (GB) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023094830-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | LARIO THERAPEUTICS LIMITED (GB) | 2023-06-01 | — | — | WO | disclosed |