Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785031 | 1.00 | IDO1 (0.48) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL19138728 | 0.86 | IDO1 (0.36) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL29643177 | 0.86 | IDO1 (0.36) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL1847891 | 0.81 | IDO1 (0.46) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL10929233 | 0.81 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL3365419 | 0.81 | IDO1 (0.48) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL16200772 | 0.79 | IDO1 (0.43) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL11957893 | 0.78 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9MAPK1 | |
| SCHEMBL28789527 | 0.78 | TSHR (0.50) | SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL28285795 | 0.77 | MAPK1 (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512520-B | P2RX7 modulators in therapy | 国家科学研究中心 | 2023-10-24 | — | — | CN | disclosed |
| CN-112020525-B | Adducts of amine catalysts for preparing isocyanurate polymers | 科思创知识产权两合公司 | 2023-05-16 | — | — | CN | disclosed |