Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL1860329 | 1.00 | CA4 (0.47) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL1865342 | 0.93 | CA4 (0.41) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL5321354 | 0.93 | — | — | |
| Glycine SCHEMBL2184513 | 0.93 | CA4 (0.53) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL10725312 | 0.93 | CA4 (0.53) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL27196 | 0.93 | — | — | |
| Glycine SCHEMBL20854477 | 0.90 | CA1 (0.60) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL6871848 | 0.89 | — | — | |
| Glycine SCHEMBL29962870 | 0.89 | CA4 (0.50) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Glycine SCHEMBL2405749 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4453162-A1 | COMPOSITIONS COMPRISING MULTIPLE CHARGED CATIONIC COMPOUNDS FOR SOIL RELEASE | Ecolab USA Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122196-A1 | COMPOSITIONS COMPRISING MULTIPLE CHARGED CATIONIC COMPOUNDS FOR SOIL RELEASE | ECOLAB USA INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20230192929-A1 | COMPOSITIONS COMPRISING MULTIPLE CHARGED CATIONIC COMPOUNDS FOR SOIL RELEASE | ECOLAB USA INC. | 2023-06-22 | — | — | US | disclosed |