Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 3/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 6/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 6/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25637936 | 1.00 | RHEB (0.48) | RHEBPKN1PKN2MAPK13PLK4 | |
| SCHEMBL783767 | 0.85 | PI4KA (0.50) | GAAPARP1BRAFKDM4EALDH1A1 | |
| SCHEMBL783583 | 0.85 | PARP1 (0.47) | MAPK13CHEK2GSK3AMAPK12MAPK11 | |
| SCHEMBL10668287 | 0.77 | CSF1R (0.43) | RHEBPKN1PKN2MAPK13PLK4 | |
| SCHEMBL10669485 | 0.77 | MGAM (0.42) | RHEBPKN1PKN2MAPK13PLK4 | |
| SCHEMBL783584 | 0.77 | PARP1 (0.53) | MAP4K4STK3MGAMGAASI | |
| SCHEMBL10670258 | 0.75 | MGAM (0.40) | RHEBPKN1PKN2MAPK13PLK4 | |
| SCHEMBL10662774 | 0.75 | JAK3 (0.44) | ROCK2STK3ROCK1KDM4EALDH1A1 | |
| SCHEMBL10669148 | 0.75 | CSF1R (0.42) | RHEBPKN1PKN2MAPK13PLK4 | |
| SCHEMBL2371989 | 0.74 | JAK2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098699-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-06-08 | — | — | WO | disclosed |