Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.61 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17994184 | 0.91 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL3030583 | 0.87 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL13456402 | 0.85 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL3047385 | 0.84 | CNR2 (0.85) | CNR2CNR1 | |
| SCHEMBL3047199 | 0.84 | CNR2 (0.78) | CNR2CNR1 | |
| SCHEMBL3036383 | 0.77 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL17994183 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3039967 | 0.72 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3030584 | 0.70 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3227178 | 0.70 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222386-A1 | SUBSTITUTED PIPERIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | US | disclosed |
| US-7767695-B2 | Substituted piperidines | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| EP-1434765-B1 | SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING TO HISTAMINE H3-RECEPTOR | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222386-A1 | SUBSTITUTED PIPERIDINES | HRH3, HRH4, HRH2 | CNR2 15/4885CNR1 19/4885DHODH 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.