Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 19/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.46 |
| ▸ | ATRIP | Q8WXE1 | 12/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25287322 | 1.00 | ATR (0.52) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL25249667 | 1.00 | ATR (0.52) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL25243745 | 0.82 | MTOR (0.48) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL25292440 | 0.82 | MTOR (0.48) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL25287665 | 0.81 | ATR (0.43) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL25293141 | 0.81 | ATR (0.56) | ATRATRIPMTORATMNUAK1 | |
| SCHEMBL30443438 | 0.81 | ATR (0.56) | ATRATRIPMTORATMNUAK1 | |
| SCHEMBL25293142 | 0.81 | ATR (0.56) | ATRATRIPMTORATMNUAK1 | |
| SCHEMBL25242204 | 0.81 | ATR (0.43) | ATRCHEK1ATRIPMTORPDCD1 | |
| SCHEMBL30443159 | 0.81 | ATR (0.43) | ATRCHEK1ATRIPMTORPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761804-B | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-116761804-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116283960-A | Substituted condensed heterocyclic compound, preparation method and application thereof | 上海安诺达生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |