⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661972 | 0.50 | — | — | |
| SCHEMBL12020220 | 0.43 | — | — | |
| SCHEMBL2178472 | 0.38 | — | — | |
| SCHEMBL1468768 | 0.38 | — | — | |
| SCHEMBL282506 | 0.35 | — | — | |
| SCHEMBL27459101 | 0.35 | — | — | |
| SCHEMBL9043609 | 0.34 | — | — | |
| SCHEMBL18329313 | 0.34 | — | — | |
| SCHEMBL18205013 | 0.34 | — | — | |
| SCHEMBL6926611 | 0.34 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239892-A1 | COMPOUNDS FOR MODULATION OF CD68 AND USES THEREOF | ARKUDA THERAPEUTICS (US) | 2023-12-14 | — | — | WO | claimed |
| EP-3724188-B1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2023-06-07 | — | — | EP | claimed |
| US-20230115534-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS | 2023-04-13 | — | — | US | claimed |
| US-20220409593-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS | 2022-12-29 | — | — | US | claimed |
| CN-114702477-A | Piperazine bridged nitroimidazole naphthalimide compound and preparation method and application thereof | 西南大学 | 2022-07-05 | — | — | CN | claimed |
| CN-108884029-B | LSD1 inhibitors | 米拉蒂医疗股份有限公司 | 2021-10-26 | — | — | CN | claimed |
| EP-3350178-B1 | NOVEL IMIDAZO [4,5-C]QUINOLINE AND IMIDAZO [4,5-C][1,5]NAPHTHYRIDINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2021-10-20 | — | — | EP | claimed |
| WO-2021127303-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2021-06-24 | — | — | WO | claimed |
| US-20210163471-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS | 2021-06-03 | — | — | US | claimed |
| WO-2021081272-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2021-04-29 | — | — | WO | claimed |
| EP-0150433-B1 | PROCESS FOR THE PREPARATION OF INSATURATED KETONES | BASF Aktiengesellschaft (DE) | 1986-12-30 | — | — | EP | claimed |
| EP-0197230-A1 | Imidazo[1,2-a]pyrimidines and their salts with the acids, process and intermediates for their preparation, use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1986-10-15 | — | — | EP | claimed |
| EP-0150433-A2 | Process for the preparation of insaturated ketones | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | claimed |
| US-4297355-A | (1H,3H,5H)-(1)-Benzopyrano-(2,3-d)-pyrimidine-4-one-2-thiones and their use as anti-allergy agents | SCHERING CORPORATION (US) | 1981-10-27 | — | — | US | claimed |
| EP-0008277-B1 | BENZOPYRANO DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR PREPARING THE COMPOUNDS AND COMPOSITIONS | Technobiotic Ltd. (CH) | 1981-09-02 | — | — | EP | claimed |
| EP-0029934-A1 | Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions | SCHERING CORPORATION (US) | 1981-06-10 | — | — | EP | claimed |
| US-4272535-A | 2,4-[1H,3H,5H]-(1)-Benzopyrano-[2,3-d]-pyrimidinediones and their use as anti-allergy agents | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | claimed |
| EP-0008277-A1 | Benzopyrano derivatives, pharmaceutical compositions containing them and processes for preparing the compounds and compositions | Technobiotic Ltd. (CH) | 1980-02-20 | — | — | EP | claimed |
| US-4162251-A | Process for the preparation of β-lactam compounds | SANKYO COMPANY LIMITED (JP) | 1979-07-24 | — | — | US | claimed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | claimed |