Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387696 | 1.00 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL25387690 | 1.00 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL26248330 | 1.00 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL26249672 | 0.94 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL25387637 | 0.94 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL25387632 | 0.94 | SCN9A (0.54) | SCN9AKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL25388198 | 0.93 | SCN9A (0.49) | SCN9ACHRM4PRMT5WDR77SLC18A3 | |
| SCHEMBL25388201 | 0.93 | SCN9A (0.49) | SCN9ACHRM4PRMT5WDR77SLC18A3 | |
| SCHEMBL25387407 | 0.91 | SCN9A (0.49) | SCN9ACHRM4PRMT5WDR77SLC18A3 | |
| SCHEMBL25387405 | 0.91 | SCN9A (0.49) | SCN9ACHRM4PRMT5WDR77SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116113626-A | Compound with anti-tumor activity and application thereof | 上海翊石医药科技有限公司 | 2023-05-12 | — | — | CN | disclosed |