SCHEMBL30444359

SCHEMBL30444359

N#Cc1cnc(Cl)cc1C(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.53
PGR P06401 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1536118 1.00 AR (0.53) ARPGR
SCHEMBL30396988 0.87 AR (0.43) AR
SCHEMBL19844883 0.87 AR (0.43) AR
SCHEMBL14932518 0.79 AR (0.56) ARPGR
SCHEMBL30485052 0.79 AR (0.56) ARPGR
SCHEMBL25331212 0.79 AR (0.54) ARPGR
SCHEMBL30485063 0.79 AR (0.56) ARPGR
SCHEMBL15878747 0.78 AR (0.53) ARPGR
SCHEMBL27953801 0.78 AR (0.53) ARPGR
SCHEMBL3840400 0.76 PIK3R1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678463-B Substituted nitrogen-containing compounds 百时美施贵宝公司 2023-06-06 CN disclosed