SCHEMBL30444569

SCHEMBL30444569

Cc1cc(-n2cc(C=O)cn2)ncc1C#N

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 20/20 0.42
KCNH2 Q12809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20574979 1.00 KCNJ1 (0.42) KCNJ1KCNH2
SCHEMBL20168622 0.89 KCNJ1 (0.42) KCNJ1KCNH2
SCHEMBL30751811 0.89 KCNJ1 (0.42) KCNJ1KCNH2
SCHEMBL20575096 0.88 KCNJ1 (0.40) KCNJ1KCNH2
SCHEMBL30445084 0.88 KCNJ1 (0.40) KCNJ1KCNH2
SCHEMBL30445140 0.84 GRM5 (0.37) KCNJ1KCNH2
SCHEMBL20168333 0.84 GRM5 (0.37) KCNJ1KCNH2
SCHEMBL24135269 0.81 KCNJ1 (0.41) KCNJ1KCNH2
SCHEMBL20575126 0.81 KCNJ1 (0.46) KCNJ1KCNH2
SCHEMBL30445164 0.81 KCNJ1 (0.46) KCNJ1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678463-B Substituted nitrogen-containing compounds 百时美施贵宝公司 2023-06-06 CN disclosed