Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20575115 | 1.00 | GRIN2D (0.35) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL23586623 | 0.87 | GRIN2D (0.36) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL28358602 | 0.78 | NPC1 (0.31) | — | |
| SCHEMBL20575020 | 0.77 | MAPK8 (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL18586335 | 0.76 | RECQL (0.41) | — | |
| SCHEMBL20168528 | 0.75 | MTOR (0.35) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL30445068 | 0.75 | MTOR (0.35) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL20574433 | 0.74 | KCNJ1 (0.37) | — | |
| SCHEMBL30444737 | 0.74 | KCNJ1 (0.37) | — | |
| SCHEMBL26543089 | 0.72 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678463-B | Substituted nitrogen-containing compounds | 百时美施贵宝公司 | 2023-06-06 | — | — | CN | disclosed |