Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507834 | 1.00 | KMT2A (0.41) | KMT2AKDM4EPTGDR2CYP1A2MAPK1 | |
| SCHEMBL28510500 | 0.85 | CYP1A2 (0.40) | KMT2AKDM4EPTGDR2CYP1A2MAPK1 | |
| SCHEMBL28506533 | 0.79 | CYP1A2 (0.46) | KMT2AKDM4ECYP1A2CYP3A4TDP1 | |
| SCHEMBL9788865 | 0.79 | CYP3A4 (0.44) | CYP1A2MAPK1CYP3A4TDP1CYP2A6 | |
| SCHEMBL28515294 | 0.78 | CYP3A4 (0.39) | CYP1A2CYP3A4TDP1CYP2A6ALDH1A1 | |
| SCHEMBL28294651 | 0.78 | PSMB5 (0.45) | KMT2AKDM4EPTGDR2CYP3A4TDP1 | |
| SCHEMBL29125468 | 0.77 | SERPINE1 (0.40) | KMT2AKDM4ECYP1A2CYP3A4MEN1 | |
| SCHEMBL29635182 | 0.76 | TDP1 (0.50) | KDM4EMAPK1CYP3A4TDP1CYP2A6 | |
| SCHEMBL4004840 | 0.76 | TDP1 (0.50) | KDM4EMAPK1CYP3A4TDP1CYP2A6 | |
| SCHEMBL2159642 | 0.76 | CYP3A4 (0.41) | KDM4ECYP1A2CYP3A4TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666961-B | Preparation method of meta-substituted biaryl tertiary phosphine ligand | 湖北大学 | 2023-05-16 | — | — | CN | disclosed |