Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCR | P30988 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 8/20 | 0.43 |
| ▸ | FNTB | P49356 | 8/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445405 | 0.93 | FNTA (0.44) | FNTAFNTBMMEPGGT1B | |
| SCHEMBL31633226 | 0.89 | NPY1R (0.42) | FNTAFNTBMMEPGGT1B | |
| SCHEMBL30445380 | 0.88 | BACE1 (0.47) | CALCRBACE1FNTAFNTBAPLNR | |
| SCHEMBL29590286 | 0.87 | FNTA (0.43) | BACE1FNTAFNTBAPLNRPGGT1B | |
| SCHEMBL29558318 | 0.87 | FNTA (0.47) | CALCRBACE1FNTAFNTBAPLNR | |
| SCHEMBL30629003 | 0.86 | NPY1R (0.46) | FNTAFNTBMMEPGGT1B | |
| SCHEMBL30445774 | 0.85 | CALCR (0.48) | CALCRBACE1FNTAFNTBAPLNR | |
| SCHEMBL30445017 | 0.85 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL30445727 | 0.85 | FNTA (0.43) | FNTAFNTBPGGT1B | |
| SCHEMBL30445417 | 0.85 | FNTA (0.43) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |